Do you always get spam sent to some other name at your email address ? Here's a great SA rule to stop that.
header NAMEWRONG To =~ /(?i)(?!.[^"]*your first name[^"]*)[^\<]*\<your\@email.com\>/
score NAMEWRONG 4.0
Just replace your name with your first name and your\@email.com with your email address. The \ is required.
I suspect this one rule will slash my spam count.
You'll need to write more rules for any regularly spammed addresses.
Edit:Hmmm.... While useful, it doesn't look like this traps that much spam.